Analysis of the active components of silymarin.
نویسندگان
چکیده
Silymarin is an antihepatotoxic substance isolated from fruits of Silybum marianum. Possibly due to their antioxidant and membrane stabilizing properties, the compounds have been shown to protect different organs and cells against a number of insults. The content and composition of main silymarin components (silybin, isosilybin, silydianin and silychristin) in various pharmaceuticals were analysed using HPLC and newly developed capillary zone electrophoresis method. Antioxidant properties expressed as total antioxidant status (TAS) of silymarin components were studied. Results of TAS were correlated with electropherograms and chromatograms.
منابع مشابه
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متن کاملOptimization of extraction of Silybum marianum fruits, presentation of three formulations of its active chemicals and designing a dissolution test method for silymarin tablet
The milk thistle of commerce is a standardized preparation extracted from fruits of Silybum marianum, a plant native to the Mediterranean. Silybum marianum extraction has been shown to be amazingly effective at protecting and repairing liver cells. We studied quality of Silymarin distribution in Silybum marianum fruits and methods of increasing out put of extracting. We formulated the extract a...
متن کاملOptimization of extraction of Silybum marianum fruits, presentation of three formulations of its active chemicals and designing a dissolution test method for silymarin tablet
The milk thistle of commerce is a standardized preparation extracted from fruits of Silybum marianum, a plant native to the Mediterranean. Silybum marianum extraction has been shown to be amazingly effective at protecting and repairing liver cells. We studied quality of Silymarin distribution in Silybum marianum fruits and methods of increasing out put of extracting. We formulated the extract a...
متن کاملاثرات آنتی‌اکسیدانی عصارۀ هیدروالکلی گیاه ماریتیغال (Silymarin) بر پاسخ مارکرهای استرس اکسیداتیو ناشی از یک جلسه فعالیت وامانده‌ساز هوازی در مردان فعال
Background and Objective: Silybum marianum has antioxidant, stabilizes cell membranes and regulate cell permeability properties. The aim of this study was to determining the effect of short-term silymarin supplementation on some of antioxidant (GPx and SOD) and oxidative stress (MDA) indices response in serum active men after one-session exhaustive aerobic exercise. Materials and Methods...
متن کاملتتأثیر مکمّل‌دهی کوتاه‌مدت عصاره‌ی هیدروالکلی گیاه خار مریم (سیلی‌مارین) بر تغییرات سطوح آنزیم‌های کبدی ناشی از یک وهله فعّالیت هوازی در مردان فعّال
Introduction: Milk Thistle is a traditional herbal medicine that contains some active ingredients including Silymarin. The aim of this study was to investigate the effect of short term silymarin supplementation on aspartate aminotransferase (AST), alanine aminotransaminase (ALT) and alkaline phosphatase (ALP) serum levels induced by one-bout aerobic exercise in active male. Methods: In a exp...
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ورودعنوان ژورنال:
- Journal of chromatography. A
دوره 990 1-2 شماره
صفحات -
تاریخ انتشار 2003